Monoclonal Antibodies Preventing Invasion of Neospora caninum Tachyzoites into Host Cells
نویسندگان
چکیده
منابع مشابه
Susceptibility of various cell lines to Neospora caninum tachyzoites cultivation
Neospora caninum is a coccidian protozoan parasite which is a major cause of bovine abortions and neonatal mortality in cattle, sheep, goat and horse. Occasionally, cultured cells are used for isolation and multiplication of the agent in vitro with several purposes. In this study the tachyzoite yields of N. caninum were compared in various cell cultures as the host cell lines. Among the cell cu...
متن کاملsusceptibility of various cell lines to neospora caninum tachyzoites cultivation
neospora caninum is a coccidian protozoan parasite which is a major cause of bovine abortions and neonatal mortality in cattle, sheep, goat and horse. occasionally, cultured cells are used for isolation and multiplication of the agent in vitro with several purposes. in this study the tachyzoite yields of n. caninum were compared in various cell cultures as the host cell lines. among the cell cu...
متن کاملIntrauterine Neospora caninum inoculation of heifers and cows using contaminated semen with different numbers of tachyzoites.
OBJECTIVE To investigate the potential of different Neospora caninum tachyzoite doses to infect heifers (experiment 1) and cows (experiment 2) when administered in utero by artificial insemination via contaminated semen. METHODS In experiment 1, five groups of 5, 7, 8, 9, and 5 cyclic heifers were hormonally synchronized and artificially inseminated with semen containing 0 (A, controls), 10(2...
متن کاملIn vitro effects of novel ruthenium complexes in Neospora caninum and Toxoplasma gondii tachyzoites.
Upon the screening of 16 antiproliferative compounds against Toxoplasma gondii and Neospora caninum, two hydrolytically stable ruthenium complexes (compounds 16 and 18) exhibited 50% inhibitory concentrations of 18.7 and 41.1 nM (T. gondii) and 6.7 and 11.3 nM (N. caninum). To achieve parasiticidal activity with compound 16, long-term treatment (22 to 27 days at 80 to 160 nM) was required. Tran...
متن کاملPrevalence of antibodies to Neospora caninum in dogs.
Serum samples from 1077 dogs suspected of having Neospora caninum infections from 35 states in the United States and 3 provinces in Canada were tested for N. caninum IgG antibodies by the indirect fluorescent antibody test. Antibodies to N. caninum were found in 75 of 1077 (7%) of the samples. Twenty of the positive dogs were females, 17 were males and the sex was not recorded on 38 dogs. Chi s...
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ژورنال
عنوان ژورنال: Journal of Veterinary Medical Science
سال: 2004
ISSN: 0916-7250,1347-7439
DOI: 10.1292/jvms.66.1355